KRAS (G12C), Isoform A, BODIPY-GDP Loaded, His-Tag 100537 from BPS Bioscience, Inc.

Description

Human KRAS also known as C-K-RAS, CFC2, and K-RAS2A with G12C mutation and N-terminal His-tag, GenBank Accession No. NM_033360, a.a. 2-186, expressed in an E. coli expression system. MW=23 kDa. KRAS (G12C) His-Tag (BPS Bioscience #100413), is loaded with BODIPY-GDP. Unbound BODIPY-GDP was removed by spin column and it is ready for the GDP/GTP exchange assay

Product Specs
ItemKRAS (G12C), Isoform A, BODIPY-GDP Loaded, His-Tag
CompanyBPS Bioscience, Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog Number100537
Quantity20 µg
Conjugate/TagN-terminal His-tag
Molecular Weight23 kDa
SpeciesHuman
Domain/Region/Terminus2-186
NCBI Full Gene NameKRAS proto-oncogene, GTPase
NCBI Gene AliasesOES, NS, KRAS1, KRAS2, KI-RAS, K-RAS4A, c-Ki-ras2, c-Ki-ras, K-RAS4B, RASK2, K-RAS2B, K-RAS2A, RALD, K-Ras 2, C-K-RAS, K-Ras, CFC2, NS3, 'C-K-RAS
TypeProtein
Format20 mM HEPES, pH 7.4, 150 mM NaCl, and 1 mM DTT
ApplicationsUseful for nucleotide exchange assay, KRAS(G12C) inhibitors screening, and selectivity profiling